Author

Sara Evke

SUNY Polytechnic InstituteORCID 0000-0002-9972-9496Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Juan Andres MelendeziD· 2 shared Thomas J. BegleyiD· 2 shared Andrea LeonardiiD· 1 shared Laura S. Van WinkleiD· 1 shared Lauren EndresiD· 1 shared Lei YiniD· 1 shared Nataliia Kovalchuk· 1 shared Peter C. DedoniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Juan Andres MelendezORCID

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2 papers

Recent·Most cited

Epitranscriptomic reprogramming is required to prevent stress and damage from acetaminophen

Sara Evke, Juan Andres Melendez, Qishan Lin, Thomas J. Begley

This study shows that acetaminophen induces epitranscriptomic reprogramming, and Alkbh8 is critical for regulating selenoprotein production and mitigating APAP toxicity.

Genes · Feb 25, 2022Peer-reviewedMolecular Biology

Epitranscriptomic regulation of the response to the air pollutant naphthalene in mouse lungs: from the perspectives of specialized translation and tolerance linked to the writer ALKBH8

Andrea Leonardi, Nataliia Kovalchuk, Lei Yin, Lauren Endres, Sara Evke, Steven Nevins, Samuel Martín, Peter C. Dedon, Juan Andres Melendez, Laura S. Van Winkle, Qing-Yu Zhang, Xinxin Ding, Thomas J. Begley

This study investigates the role of ALKBH8 in protecting mouse lungs from naphthalene toxicity, showing increased sensitivity in its deficiency and a protective effect on lung function.

bioRxiv · Aug 7, 2019 · PreprintMolecular Biology