Johannes Benjamin Holle

This study identifies IL-17A as a mediator of oxalate-induced cardiorenal injury in CKD, showing its role in inflammation and cardiac dysfunction.

This study identifies a microbiome-AhR-IL-17A axis that drives CKD-associated cardiac fibrosis and shows that AhR inhibition prevents remodeling.

The paper shows that T cells from treatment-resistant hypertension patients worsen hypertension and endothelial dysfunction in humanized mice through TNF.