Alma Zernecke

The paper shows that promoting soluble FLT1 over full-length FLT1 enhances postischemic angiogenesis by modulating gene isoform expression through APA.

This study shows TREM2 drives pro-scarring macrophage accumulation in infarcted myocardium, leading to fibrosis and reduced cardiac repair.

This study identifies IL-17A as a mediator of oxalate-induced cardiorenal injury in CKD, showing its role in inflammation and cardiac dysfunction.

This study identifies a microbiome-AhR-IL-17A axis that drives CKD-associated cardiac fibrosis and shows that AhR inhibition prevents remodeling.

This study shows that neutrophils in the ischemic heart undergo terminal programming to drive fibrosis after myocardial infarction.

This study identifies molecular and cellular changes in cardiac lymphatics during pressure-overload, showing valve loss and barrier dysfunction in BALB/c mice but not C57BL/6J.

This study identifies blood endothelial cells in secondary lymphoid organs as key APCs that prime donor CD4 T cells, leading to acute graft-versus-host disease.

The paper shows that U1 snRNP-dependent intronic polyadenylation suppresses miRNA biogenesis in melanoma by altering TRPM1 alternative polyadenylation signals.