Marcelo R. S. Briones

The paper detects HPV16 in ancient human genomes from Ust'-Ishim and Ötzi, showing its presence in modern humans during the Upper Paleolithic.

This paper uses machine learning on direct RNA-seq data to show SARS-CoV-2 increases mA methylation in antiviral lncRNAs, potentially affecting IFN signaling and viral persistence.

This study identifies mitochondrial genome variants associated with ALS and reports haplogroup distribution patterns in ALS patients.

The paper identifies viral genome remnants in Neanderthal sequencing data by mapping to adenovirus, herpesvirus, and papillomavirus, showing divergence consistent with their age and viral evolutionary rates.

The paper identifies 66 Neanderthal single nucleotide variants in modern human mitochondrial genomes, suggesting convergent evolution rather than recombination.

The paper uses direct RNA sequencing to identify m6A sites and analyze DRACH motif methylation differences in SARS-CoV-2 variants.

The paper infers the evolution of mitochondrial genomes in yeasts using phylogenomic supertrees and supermatrices, showing complex I loss predates a whole genome duplication and occurred independently in two yeast lineages.

The paper investigates the role of PAFR in ALS and suggests PAFR inhibitors as potential therapeutic agents, particularly for SOD1 familial ALS.

This study identifies co-evolving bacteria in Candida albicans cultures from single colonies, showing their presence is missed in standard clinical testing due to short incubation times and media.

This study evolves Candida albicans under hypoxia and heat shock, finding nuclear genome variants and reduced mtDNA methylation without mtDNA sequence changes.