Author

Cristina Sáenz de Miera

University of MichiganORCID 0000-0001-8047-035XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Carol Fuzeti EliasiD· 3 shared Nicole Bellefontaine· 3 shared José DonatoiD· 2 shared Kevin W. WilliamsiD· 2 shared Marina Augusto SilveiraiD· 2 shared Renata FrazãoiD· 2 shared Thais T. ZampieriiD· 2 shared Chelsea N. FortiniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Carol Fuzeti EliasORCID

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3 papers

Recent·Most cited

Nutritionally responsive PMv DAT neurons are dynamically regulated during pubertal transition

Cristina Sáenz de Miera, Nicole Bellefontaine, Marina Augusto Silveira, Chelsea N. Fortin, Thais T. Zampieri, José Donato, Kevin W. Williams, Cristiano Mendes‐da‐Silva, Laura Heikkinen, Christian Broberger, Renata Frazão, Carol Fuzeti Elias

This study identifies PMvDAT neurons as a leptin-responsive subpopulation in the hypothalamus that dynamically regulates sexual maturation during puberty.

The FASEB Journal · Jun 27, 2025Peer-reviewedNeuroscience

Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice

Cristina Sáenz de Miera, Nicole Bellefontaine, Susan J. Allen, Martin Grosvenor Myers, Carol Fuzeti Elias

This study shows that glutamatergic signaling from leptin-responsive PMv neurons is essential for puberty and reproductive function in female mice.

eLife · Jul 15, 2024Peer-reviewedNeuroscience

Reproductive neuronal circuitry in adaptive changes of energy balance

Pilhwa Lee, Cristina Sáenz de Miera, Nicole Bellefontaine, Marina Augusto Silveira, Thais T. Zampieri, José Donato, Kevin W. Williams, Renata Frazão, Carol Fuzeti Elias

The paper identifies leptin-hyperpolarized neurons in the PMv that coexpress DAT and prolactin receptor, and shows they inhibit reproduction via AgRP, with computational modeling linking these findings to metabolic control of reproduction.

bioRxiv · Sep 9, 2021 · PreprintNeuroscience