Molecular BiologyJournal of Cell SciencePeer-reviewed
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS
Natalie E. Farrawell, Isabella A. Lambert-Smith, Kristen Mitchell…·Justin J. Yerbury
This study shows that SOD1A4V aggregation disrupts ubiquitin homeostasis in an ALS cell model, leading to UPS dysfunction and altered mitochondrial function.
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