Author

Darren N. Saunders

UNSW SydneyORCID 0000-0003-0924-0513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Burgess· 1 shared Isabella A. Lambert-SmithiD· 1 shared Jessie A. McKenna· 1 shared Jessie McKenna· 1 shared Justin J. YerburyiD· 1 shared Kara L. VineiD· 1 shared Kari-Anne Myrum Frikstad· 1 shared Kristen Mitchell· 1 shared

Activity by Year

2016-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Andrew Burgess

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2 papers

Recent·Most cited

Molecular BiologyJournal of Cell SciencePeer-reviewedMay 10, 2018

SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS

Natalie E. Farrawell, Isabella A. Lambert-Smith, Kristen Mitchell…·Justin J. Yerbury

This study shows that SOD1A4V aggregation disrupts ubiquitin homeostasis in an ALS cell model, leading to UPS dysfunction and altered mitochondrial function.

58 citationstop 4%

humanproteomics

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Cell BiologybioRxivPreprintDec 22, 2016

The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia formation via ubiquitylation of CSPP-L.

Robert F. Shearer, Kari-Anne Myrum Frikstad, Jessie McKenna…·Darren N. Saunders

This study identifies UBR5 as an E3 ubiquitin ligase that regulates primary cilia formation by ubiquitylating CSPP1, affecting centriolar satellite stability.

DOI 10.1101/090100

humanproteomics

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