Erika McCarthy

This paper investigates the role of a third metal ion in the catalytic cycle of a group I intron ribozyme using computational methods and proposes design modifications to expand its sequence compatibility.

This study identifies conformational and electronic factors governing SAMURI ribozyme catalysis using computational methods, showing that reactivity depends on minor reactive conformations and electronic properties of cofactors.

The paper analyzes 3D structural changes in SARS-CoV-2 proteins during the first six months of the pandemic, showing amino acid substitutions primarily affect surfaces and boundary layers.