Author

Christine Zardecki

Rutgers, The State University of New JerseyORCID 0000-0002-4149-1745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Brian P. HudsoniD· 2 shared Joseph H. LubiniD· 2 shared Sagar D. KhareiD· 2 shared Stephen Kevin BurleyiD· 2 shared Aaliyah KhaniD· 1 shared Alan Trudeau· 1 shared Ali A. KhaniD· 1 shared Allison Rupert· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Brian P. HudsonORCID

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2 papers

Recent·Most cited

A comprehensive survey of coronaviral main protease active site diversity in 3D: Identifying and analyzing drug discovery targets in search of broad specificity inhibitors for the next coronavirus pandemic

Joseph H. Lubin, Samantha G. Martinusen, Christine Zardecki, Cassandra Olivas, Mickayla Bacorn, Mary-Agnes Balogun, Ethan W Slaton, Amy Wu Wu, Sarah Sakeer, Brian P. Hudson, Carl A. Denard, Stephen Kevin Burley, Sagar D. Khare

The paper analyzes the diversity of coronaviral main protease active sites to identify potential broad-spectrum inhibitors for future pandemics.

bioRxiv · Jan 30, 2023 · PreprintMolecular Biology

Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

Joseph H. Lubin, Christine Zardecki, Elliott M. Dolan, Changpeng Lu, Zhuofan Shen, Shuchismita Dutta, John Westbrook, Brian P. Hudson, David S. Goodsell, Jonathan K. Williams, Maria Voigt, Vidur Sarma, Lingjun Xie, Thejasvi Venkatachalam, Steven Arnold, , Stephen Kevin Burley

The paper analyzes 3D structural changes in SARS-CoV-2 proteins during the first six months of the pandemic, showing amino acid substitutions primarily affect surfaces and boundary layers.

bioRxiv · Dec 1, 2020 · PreprintMolecular Biology