Şölen Ekesan

This paper investigates the role of a third metal ion in the catalytic cycle of a group I intron ribozyme using computational methods and proposes design modifications to expand its sequence compatibility.

This study identifies conformational and electronic factors governing SAMURI ribozyme catalysis using computational methods, showing that reactivity depends on minor reactive conformations and electronic properties of cofactors.

This study determines the structural plasticity of HIV-1 RRE stem-loop II and shows how it modulates Rev binding and nuclear export of viral RNA.