Kishore R. Alugupalli

This study develops a TLR4 ligand-based adjuvant, Turbo, which enhances the immunogenicity of typhoid ViPS vaccines in mice, improving antibody responses and bacterial control across ages.

This study shows CD271 restrains B1b cell antibody responses to T cell-independent antigens by maintaining CD4+ T cell quiescence and inhibiting T cell activity, similar to PD-L1.