Giansimone Perrino

The paper presents a coarse-grained E. coli cell model to analyze and design synthetic gene circuits by capturing resource couplings and growth regulation mechanisms.

This paper develops a cyber-genetic system to achieve long-term cell cycle synchronization in yeast using closed-loop feedback control.

ChipSeg segments bacterial and mammalian cells in microfluidic devices using thresholding, enabling fluorescence quantification and cell tracking in time-lapse experiments.

This paper proposes a strategy to synchronize yeast cell cycles using quorum sensing, modeled with ordinary differential equations.

The paper designs control strategies to synchronize yeast cell cycles using methionine levels, validated both in silico and experimentally.

This paper develops and evaluates feedback control strategies to synchronize the cell cycle in yeast populations while minimizing volume growth.