Author
Chinese University of Hong Kong, ShenzhenORCID 0000-0001-8107-6397Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Feng Hong, Jingyi Wang, Dongsheng Chen…·Zuxin Chen
This paper develops a novel peripherally acting alpha2A-adrenergic receptor antagonist, CDS479-2, which improves glucose control in diabetic mice without central side effects.
Wei Gao, Shiyi Gan, Mengting Zhang…·Honglin Li
The paper determines the cryo-EM structure of activated S1PR4, revealing mechanisms of ligand recognition and Gi coupling to aid in developing safer S1PR4 agonists.
Donghoon Ahn, Davide Provasi, Nguyen Minh Duc…·Ka Young Chung
The paper characterizes the conformational changes in the Gαs protein upon GTP binding and identifies a novel regulator, MAGE D2, using a Bayesian integrative modeling approach.