Qing Yun Li

The paper identifies a novel SOX9 variant in the TAM domain linked to axial skeletal dysplasia and scoliosis, showing reduced protein stability and recapitulating human phenotypes in mice.

The paper investigates how progesterone induces heritable pulmonary arterial hypertension in BMPR2 mutation carriers, showing it promotes PASMC proliferation via ERK pathway activation.

This study shows that Compound 42 inhibits pancreatic tumor growth by inducing ferroptosis and arresting the cell cycle in pancreatic cancer cells.

bMSI-CAST improves cfDNA MSI detection by enhancing locus selection, duplicate removal, and calling algorithm, achieving high accuracy in gastrointestinal cancer samples.