Robert M Flight

The paper identifies PLK1-mediated phosphorylation of PHGDH as a mechanism driving serine metabolism reprogramming in advanced prostate cancer, increasing reliance on exogenous serine uptake.

The recount3 Python package provides programmatic access to uniformly processed RNA-seq data, enabling efficient use in Python-based computational pipelines.

The paper introduces ICI-Kt, a method to interpret left-censored missing values in metabolomics as informative, improving outlier detection and network construction.

The paper improves pathway enrichment analysis of metabolomics datasets by generating high-quality predicted metabolite-pathway annotations, increasing the number of detected enriched pathways by 8-fold.

The paper introduces a scan-centric method for characterizing peaks in mass spectrometry data, improving the accuracy of isotope abundance analysis.

This paper introduces GOcats, a tool that improves gene ontology enrichment by handling relations more accurately, showing significant improvements in two gene-expression datasets.

The paper identifies and addresses high peak density artifacts in Fourier transform mass spectra, which can mislead data analysis by creating false peaks.

The paper identifies dose-dependent transcriptional biomarkers in peripheral blood lymphocytes exposed to ionizing radiation using microarray analysis.