Redox-dependent lipophilicity of phenazine metabolites is modulated by intramolecular hydrogen bonds and controls their biological distribution
Korbinian O. Thalhammer, Matthew Scurria, Jinyang Li, Inês Trindade, Osvaldo Gutiérrez, Stuart J. Conway, Dianne K. Newman
This study measures the redox-dependent lipophilicity of phenazines and shows how their redox state affects retention in bacterial cells.
ACS Chemical Biology · Aug 22, 2026Peer-reviewedBiochemistry