Author

Matthew Scurria

University of California, Los AngelesORCID 0009-0001-0598-2133Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:metabolomics· 2 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Dianne K. NewmaniD· 3 shared Korbinian O. ThalhammeriD· 3 shared Stuart J. ConwayiD· 3 shared Osvaldo GutiérreziD· 2 shared Ariane MoraiD· 1 shared Inês B. TrindadeiD· 1 shared Inês TrindadeiD· 1 shared Jinyang Li· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

Dianne K. NewmanORCID

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3 papers

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedAug 22, 2026

Redox-dependent lipophilicity of phenazine metabolites is modulated by intramolecular hydrogen bonds and controls their biological distribution

Korbinian O. Thalhammer, Matthew Scurria, Jinyang Li…·Dianne K. Newman

This study measures the redox-dependent lipophilicity of phenazines and shows how their redox state affects retention in bacterial cells.

DOI 10.1021/acschembio.6c00422

bacteria (other)metabolomics

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MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedJul 27, 2026

Discovery of a phenazine thiol conjugase from sparse data using genome-informed machine learning

Xiaoyu Shan, Inês B. Trindade, Nathaniel R. Glasser…·Dianne K. Newman

The paper uses genome-informed machine learning to discover a new enzyme, PTC, that catalyzes phenazine thioconjugation from sparse data.

DOI 10.1073/pnas.2607571123

protein sequencedeep learning

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MicrobiologyMolecular MicrobiologyPeer-reviewedJun 8, 2026

Nitric oxide tunes secreted metabolite bioactivity

Zachery R. Lonergan, Sarah L. Weisflog, Matthew Scurria…·Dianne K. Newman

This study shows nitric oxide modifies secreted metabolites' activity, reducing their antibiotic effects and causing toxicity to the producing bacteria.

DOI 10.1111/mmi.70083

bacteria (other)metabolomics

𝕏 PostBluesky