Tiemo Jürgen Klisch

This study identifies NF2 loss-of-function and hypoxia as drivers of radiation resistance in Grade 2 meningiomas through genetic, histopathological, and transcriptional analyses.

This study develops CLIPPR, an algorithm that integrates single-cell and bulk RNA-seq data to improve meningioma classification and resolve benign-malignant confusion.

This study combines bulk RNA-Seq datasets to create a transcriptomic landscape of meningiomas, identifies subtypes with distinct biology and prognosis, and provides an interactive tool for outcome prediction.

XCVATR identifies and characterizes variant impact on embeddings of single-cell and bulk RNA-seq samples by detecting local variant enrichment in embedding space.

scRegulocity detects local RNA velocity patterns in single-cell RNA-seq embeddings to identify regulatory changes and cell state transitions.