Pagé C. Goddard

This paper develops a pangenome-based method to improve trait association and genomic prediction by capturing complex genetic variation missed by traditional approaches.

The paper identifies haplospecific antisense oligonucleotides for genetic disorder treatment using population genome sequencing and haplotyping.

The paper identifies individuals with minor spliceopathies by analyzing transcriptome-wide splicing outliers in RNA-seq data from rare disease cohorts.

The paper integrates long-read sequencing and gene expression to prioritize functional structural variants and tandem repeats in rare disease patients, identifying potential causal variants in a neurodevelopmental disorder.

The paper investigates how priority effects influence gene expression in nectar yeast, finding differential expression in amino acid metabolism and eQTL enrichment for antifungal resistance.

The paper develops criteria for identifying, sharing, and reporting novel candidate genes in clinical genomic testing to improve diagnostic yield for Mendelian conditions.

This study examines how different genome builds affect RNA-seq results in rare disease samples and recommends cross-referencing with a database of build-dependent genes for more accurate transcriptomics analysis.

The paper describes the development of a course on genetics, ethics, and society designed by trainees to address the lack of ethics training in scientific education.

The paper identifies novel transcripts, eQTLs, and caQTLs in African populations and fine-maps GWAS signals for complex diseases.

This study identifies three novel genetic loci associated with pre- and post-bronchodilator lung function in African American children with asthma using integrative genomic analysis.

This study conducts the first genome-wide association study of telomere length in African American youth, finding a novel association and failing to replicate previous findings in adults and European children.

This study identifies pharmacogenetic variants associated with albuterol bronchodilator response in minority children with asthma using whole genome sequencing.