Marianne K. DeGorter

Multi-omics in the All Of Us Research Program expands mapping genetic mechanisms in health and disease

The paper reports on the All of Us multi-omics cohort, identifying 182,246 QTLs and demonstrating rare variant effects across proteomic and transcriptomic data.

Pangenome-based human genome analysis improves trait association and genomic prediction

This paper develops a pangenome-based method to improve trait association and genomic prediction by capturing complex genetic variation missed by traditional approaches.

Transcriptomics and chromatin accessibility in multiple African population samples

The paper identifies novel transcripts, eQTLs, and caQTLs in African populations and fine-maps GWAS signals for complex diseases.

Multiple Causal Variants Underlie Genetic Associations in Humans

This study identifies multiple causal variants underlying genetic associations in humans using MPRA and eQTL data.

Population-specific imputation of gene expression improves prediction of pharmacogenomic traits for African Americans

The paper improves warfarin dose prediction for African Americans by integrating population-specific gene expression imputation with genetic variation data.