Kevin L. Keys

The paper analyzes gene expression in African American and Latino children to show ancestry-specific genetic architecture and highlights the benefits of diverse genomic studies.

This study identifies three novel genetic loci associated with pre- and post-bronchodilator lung function in African American children with asthma using integrative genomic analysis.

The paper tests gene expression prediction models' performance across populations and finds poor generalizability to African Americans compared to European Americans.

This study evaluates cost-effective GWAS strategies combining sequencing and array genotyping to improve power and genomic coverage in diverse populations.

This paper introduces an improved iterative hard thresholding method for GWAS that enhances true positive rates and reduces false positives compared to traditional approaches.

The paper analyzes the molecular evolution of human metabolic genes, finding that pathway topology and functional class influence selective pressures, with core genes being more conserved and outer layer genes more plastic.

This study conducts the first genome-wide association study of telomere length in African American youth, finding a novel association and failing to replicate previous findings in adults and European children.

This study identifies pharmacogenetic variants associated with albuterol bronchodilator response in minority children with asthma using whole genome sequencing.