Author

Lukas P. Feilen

University of CopenhagenORCID 0000-0001-8221-6742Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Henriette Elisabeth AutzeniD· 2 shared Anton A. A. AutzeniD· 1 shared Birthe Brandt KragelundiD· 1 shared Casper de LichtenbergiD· 1 shared Charalampos SiderisiD· 1 shared Ciara Frances PughiD· 1 shared Dušan ŽivkovićiD· 1 shared Emil E. TranchantiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Henriette Elisabeth AutzenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedDec 10, 2025

MAASTY: A (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs

Ciara Frances Pugh, Lukas P. Feilen, Dušan Živković…·Henriette Elisabeth Autzen

The paper introduces MAASTY, a copolymer for extracting membrane proteins into native nanodiscs, enabling high-resolution structural analysis with cryo-EM while preserving lipids.

9 citations

𝕏 PostBluesky

BiochemistrybioRxivPreprintJul 21, 2025

Integrative structural analysis of the human endosomal Na⁺/H⁺ exchanger NHE6 reveals a lipid-stabilized intracellular gate and a disordered C-terminus

Lukas P. Feilen, Emil E. Tranchant, Milena Rankilde Lilac…·Henriette Elisabeth Autzen

The paper presents the cryo-EM structure of HsNHE6, revealing its dimeric architecture, ion-binding site, and lipid-stabilized gate, along with insights into its disordered C-terminus and functional roles in ion exchange and disease.

1 citation

𝕏 PostBluesky