Henriette Elisabeth Autzen

This paper designs a deep learning-generated hASIC1a inhibitor that reduces infarct volume by over 50% in a mouse stroke model.

The paper introduces MAASTY, a copolymer for extracting membrane proteins into native nanodiscs, enabling high-resolution structural analysis with cryo-EM while preserving lipids.

The paper presents the cryo-EM structure of HsNHE6, revealing its dimeric architecture, ion-binding site, and lipid-stabilized gate, along with insights into its disordered C-terminus and functional roles in ion exchange and disease.