Author

Ishwar N. Kohale

Koch Institute for Integrative Cancer Research At MITORCID 0000-0001-8225-1740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Forest M. WhiteiD· 3 shared Danielle M. BurgenskeiD· 2 shared Jann Nagina SarkariaiD· 2 shared Katrina K. BakkeniD· 2 shared Aimee C. MoiseiD· 1 shared Alicia D. D’SouzaiD· 1 shared Ann C. MladekiD· 1 shared Ann C. Mladek Tuma· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersSystems Biology

Forest M. WhiteORCID

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3 papers

Recent·Most cited

Systems BiologyNature CommunicationsPeer-reviewedAug 8, 2026

Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT

Ryuhjin Ahn, Alicia D. D’Souza, Lawrence Long…·Forest M. White

The paper introduces INSIGHT, a platform for phosphoproteomic analysis of rare cell subpopulations, and applies it to study signaling changes in disseminated glioblastoma cells in vivo.

1 citation

mouseproteomics

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Cancer BiologyNAR CancerPeer-reviewedApr 8, 2026

Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer

Lee J. Pribyl, Jennifer E. Kay, Joshua J. Corrigan…·Bevin P. Engelward

This study identifies persistent interferon signaling and clonal expansion as early events in NDMA-induced liver cancer by analyzing molecular changes in mice.

2 citations

mousebulk RNA-seq

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Systems BiologyCancer ResearchPeer-reviewedMay 20, 2021

Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks

Ishwar N. Kohale, Danielle M. Burgenske, Ann C. Mladek…·Forest M. White

The paper quantifies tyrosine phosphorylation in FFPE tissues to reveal patient-specific signaling networks and identifies oncogenic kinases in cancer tumors.

32 citations

humanproteomics

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