Author

Ann C. Mladek

Mayo ClinicORCID 0000-0002-0508-6531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Danielle M. BurgenskeiD· 2 shared Forest M. WhiteiD· 2 shared Jann Nagina SarkariaiD· 2 shared Bogdan I. FedelesiD· 1 shared Cécile Riviere-CazauxiD· 1 shared Elizabeth Y. Choe· 1 shared Eric B. HauraiD· 1 shared Ishwar N. KohaleiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Danielle M. BurgenskeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Systems analysis uncovers early temozolomide responses and peptide antigens in glioblastoma

Elizabeth Y. Choe, Owen K. Leddy, Cécile Riviere-Cazaux, Danielle M. Burgenske, Zeng Hu, Ann C. Mladek, Bogdan I. Fedeles, Shidong Hu, John M. Essigmann, Robert Michael Prins, Jann Nagina Sarkaria, Terry C. Burns, Rachael A. Vaubel, Forest M. White

This study uses a multi-omics approach to analyze early TMZ responses in GBM cells, identifying TMZ-associated peptide antigens and immune-related changes.

bioRxiv · Nov 10, 2025 · PreprintCancer Biology

Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks

Ishwar N. Kohale, Danielle M. Burgenske, Ann C. Mladek, Katrina K. Bakken, Jenevieve Kuang, Judy Caroline Boughey, Liewei Wang, Jodi M. Carter, Eric B. Haura, Matthew Philip Goetz, Jann Nagina Sarkaria, Forest M. White

The paper quantifies tyrosine phosphorylation in FFPE tissues to reveal patient-specific signaling networks and identifies oncogenic kinases in cancer tumors.

Cancer Research · May 20, 2021Peer-reviewedSystems Biology