Author

Li‐Kai Lin

Purdue University West LafayetteORCID 0000-0001-8232-4401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel YsselsteiniD· 1 shared Deniz KirikiD· 1 shared George P. McCabeiD· 1 shared J. C. Rochet· 1 shared Jagadish Hindupur· 1 shared John D. HullemaniD· 1 shared Katherine E. Strathearn· 1 shared Kerstin Buck· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Daniel YsselsteinORCID

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1 paper

Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedSep 8, 2020

Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

Natalie Landeck, Katherine E. Strathearn, Daniel Ysselstein…·J. C. Rochet

The paper compares neurotoxicity of human A53T and mouse α-synuclein variants, finding mouse aSyn is less toxic due to C-terminal substitutions reducing membrane-induced aggregation and vesicle permeabilization.

19 citations

humanmouse