Author

Cristian I. Ruse

New England Biolabs (United States)ORCID 0000-0001-8237-6308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Colleen M. McClungiD· 2 shared Ashley N. Luck· 1 shared Ching‐Chung KoiD· 1 shared Christopher H. TaroniD· 1 shared Elisabeth A. RaleighiD· 1 shared Fana B. MershaiD· 1 shared Graham F. HatfulliD· 1 shared Hang Gyeong Chin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetics

Colleen M. McClungORCID

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3 papers

Recent·Most cited

Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation domains in mammalian cells

Pierre‐Olivier Estève, Sagnik Sen, Udayakumar S. Vishnu, Cristian I. Ruse, Hang Gyeong Chin, Sriharsa Pradhan

This study shows that PARP1 poly ADP-ribosylates SET8, impairing its function and leading to altered H4K20 methylation domains and chromatin states.

Communications Biology · Nov 25, 2022Peer-reviewedMolecular Biology

Genome analysis of Salmonella enterica serovar Typhimurium bacteriophage L, indicator for StySA (StyLT2III) restriction-modification system action

Julie Zaworski, Colleen M. McClung, Cristian I. Ruse, Peter Weigele, Roger W. Hendrix, Ching‐Chung Ko, Robert H. Edgar, Graham F. Hatfull, Sherwood Casjens, Elisabeth A. Raleigh

The paper reports the genome sequence of bacteriophage L, compares it to related phages, and identifies features related to restriction-modification systems in Salmonella.

G3 Genes Genomes Genetics · Dec 22, 2020Peer-reviewedGenetics

Computational and experimental analysis of the glycophosphatidylinositol-anchored proteome of the human parasitic nematode Brugia malayi

Fana B. Mersha, Leslie K. Cortes, Ashley N. Luck, Colleen M. McClung, Cristian I. Ruse, Christopher H. Taron, Jeremy M. Foster

The paper characterizes the GPI-anchored proteome of Brugia malayi using computational and experimental methods, identifying potential targets for anthelmintic therapies.

PLoS ONE · Sep 12, 2019Peer-reviewedMolecular Biology