Jens‐Uwe Sommer

Repulsion-Driven Layering in Polymer-Assisted Condensation

This paper introduces Polymer-Assisted Condensation (PAC) to explain repulsion-driven layering in biomolecular condensates, showing it forms stable core-shell structures without relying on interfacial tension hierarchies.

Assembling a true "Olympic Gel" from >16,000 combinatorial DNA rings

This paper creates a true Olympic gel from over 16,000 DNA rings, showing unique mechanical properties and swelling behavior due to entanglements.

Born to Condense: Polysomes Drive Co-Translational Condensation of Biomolecular Condensate Proteins

This paper introduces a theoretical framework for co-translational condensation (CTC), showing how polysomes drive the formation of biomolecular condensates through protein synthesis.

Wetting and localization of chromatin condensates by surface-enriched proteins

The paper proposes a wetting-based mechanism for chromatin condensate localization at the nuclear lamina through surface-enriched proteins, showing nonmonotonic density profiles and regulatory effects of non-binding proteins.

The Impact of Coiled-Coil Domains on the Phase Behavior of Biomolecular Condensates

This study uses simulations to show coiled-coil domains promote liquid-liquid phase separation by preventing loop-closure defects and enabling protein networking.