Helmut Schießel

MDNA is a software module that generates and analyzes complex DNA structures, supporting modifications and providing geometric analysis tools for detailed DNA modeling.

This paper introduces Polymer-Assisted Condensation (PAC) to explain repulsion-driven layering in biomolecular condensates, showing it forms stable core-shell structures without relying on interfacial tension hierarchies.

This paper investigates how DMSO affects DNA structure and mechanics using single-molecule techniques and simulations, finding that DMSO increases DNA flexibility and compaction up to 50% concentration.