Author

Tristan M. G. Kenney

University of TorontoORCID 0000-0001-8242-4349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A.M. EdwardsiD· 1 shared Aiping DongiD· 1 shared Alma Seitova· 1 shared Bryan J. FraseriD· 1 shared C.H. ArrowsmithiD· 1 shared François BénardiD· 1 shared Gregg B. MoriniD· 1 shared Jackie Lac· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A.M. EdwardsORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 10, 2025

Structural basis of TMPRSS11D specificity and autocleavage activation

Bryan J. Fraser, Ryan P. Wilson, Sára Ferková…·C.H. Arrowsmith

The paper determines the structural basis of TMPRSS11D autocleavage activation and shows that nafamostat mesylate is cleaved by TMPRSS11D, reducing its efficacy as a protease inhibitor.

10 citations

humanstructural biology

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