Author

Sára Ferková

Université de SherbrookeORCID 0009-0002-2890-6528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Pierre‐Luc BoudreaultiD· 2 shared A.M. EdwardsiD· 1 shared Aiping DongiD· 1 shared Alma Seitova· 1 shared Avan N ColahiD· 1 shared Bryan J. FraseriD· 1 shared C.H. ArrowsmithiD· 1 shared Charles Izuchukwu EzekieliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Pierre‐Luc BoudreaultORCID

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2 papers

Recent·Most cited

Molecular BiologyFrontiers in PharmacologyPeer-reviewedSep 28, 2026

Profiling crystal engineered ligands for targeting treatment resistant androgen receptors

Avan N Colah, Charles Izuchukwu Ezekiel, Sára Ferková…·William A. Ricke

This study develops and evaluates crystal-engineered ligands (CBs) for targeting treatment-resistant androgen receptors in prostate cancer, showing their potential as novel therapeutic agents.

DOI 10.3389/fphar.2026.1813002

humanexperimental assay

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BiochemistryNature CommunicationsPeer-reviewedMay 10, 2025

Structural basis of TMPRSS11D specificity and autocleavage activation

Bryan J. Fraser, Ryan P. Wilson, Sára Ferková…·C.H. Arrowsmith

The paper determines the structural basis of TMPRSS11D autocleavage activation and shows that nafamostat mesylate is cleaved by TMPRSS11D, reducing its efficacy as a protease inhibitor.

10 citations

humanstructural biology

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