MicrobiologybioRxivPreprint
NSUN2-dependent 5-methylcytosine Modification Regulates Influenza A virus Gene Expression and Genomic Packaging
Jing Hu, Shengqiang Jiang, Wanling You…·Hongying Chen
This study shows that NSUN2-dependent m5C modifications on influenza A virus RNA are essential for proper viral particle assembly and pathogenicity, suggesting m5C depletion could attenuate IAV strains.
DOI 10.1101/2025.11.26.690652