Sydney P. Thomas

This study examines how maternal antibiotic use during breastfeeding affects the infant gut microbiome and metabolome, finding altered microbial profiles and increased BMI in some infants.

The paper introduces a collaborative platform for curating microbial metabolite knowledge to enhance metabolomics data interpretation.

The paper examines how environmental and maternal factors influence infant gut metabolism through microbiome and metabolome profiling in Bangladeshi mother-infant pairs.

This study examines how maternal ampicillin exposure during pregnancy and postpartum affects fecal microbiome and metabolic profiles, linking these changes to increased offspring weight gain.

This study evaluates imputation methods for untargeted metabolomics data, finding that kNN and RF imputation perform poorly with missing data, especially MNAR, and that missing data proportion significantly affects accuracy.

The paper develops a drug exposure resource from untargeted metabolomics data to identify medications without clinical records.

This study examines how ampicillin exposure via different routes affects bile acid metabolism in mice, finding significant changes in maternal bile acids and increased infant weight.

The paper creates a suspect spectral library for untargeted metabolomics by propagating annotations from public MS/MS spectra to improve interpretation of unannotated spectra.

This study shows that TMAO reduces neurite density and amyloid-β plaque intensity in a mouse model of Alzheimer's disease.