Shirley M. Tsunoda

Effect of Perinatal Ampicillin or Amoxicillin/Clavulanate Exposure on Maternal and Infant Gut Microbiome, Metabolome, and Infant Responses to the 20-valent Pneumococcal Conjugate Vaccine

This study examines how maternal exposure to ampicillin or amoxicillin/clavulanate affects neonatal gut microbiome, metabolome, and vaccine responses to PCV20.

Antibiotic Exposure Through Human Milk Influences the Infant Gut Microbiome

This study examines how maternal antibiotic use during breastfeeding affects the infant gut microbiome and metabolome, finding altered microbial profiles and increased BMI in some infants.

Pan-Metabolomics Repository Mapping of the Carnitine Landscape

The paper systematically extracts and catalogs acylcarnitine metabolites from multiple repositories, identifying previously unknown carnitines and providing a resource for further metabolic research.

Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data

The paper introduces a collaborative platform for curating microbial metabolite knowledge to enhance metabolomics data interpretation.

Environmental and Maternal Imprints on Infant Gut Metabolic Programming

The paper examines how environmental and maternal factors influence infant gut metabolism through microbiome and metabolome profiling in Bangladeshi mother-infant pairs.

Influence of perinatal ampicillin exposure on maternal fecal microbial and metabolic profiles

This study examines how maternal ampicillin exposure during pregnancy and postpartum affects fecal microbiome and metabolic profiles, linking these changes to increased offspring weight gain.

Fecal Microbial and Metabolic Signatures in VEO-IBD: Implications for Unique Pathophysiology

This study identifies distinct microbial and metabolic signatures in VEO-IBD compared to healthy controls, linking microbiome changes to metabolic dysregulation.

Empirically establishing drug exposure records directly from untargeted metabolomics data

The paper develops a drug exposure resource from untargeted metabolomics data to identify medications without clinical records.

Perinatal ampicillin administration modulates murine bile acid metabolism in vivo - an observational study

This study examines how ampicillin exposure via different routes affects bile acid metabolism in mice, finding significant changes in maternal bile acids and increased infant weight.

Physicochemical and Pharmacokinetic Properties Determining Drug Detection in Skin

The paper uses a random forest classifier to predict which drugs are detectable on skin using metabolomics, finding that nervous system drugs are more likely to be detected.