Matthew D. Lee

The paper maps a mesoscale molecular architecture of the human striatum across cell types and age, revealing zonal differences in gene expression and aging effects.

VasoTracker 2 provides open-source software and low-cost hardware for analyzing vascular reactivity and function across multiple imaging modalities.

This study shows that increased TRPV4 channel expression in endothelial cells both enhances and impairs vascular function in hypertension, leading to altered Ca2+ signaling and vascular reactivity.