Author

John G. McCarron

University of StrathclydeORCID 0000-0002-3302-3984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Charlotte BuckleyiD· 3 shared Xun ZhangiD· 3 shared Calum WilsoniD· 2 shared Margaret MacDonald· 2 shared Matthew D. LeeiD· 2 shared Amy MacDonald· 1 shared Christine SalaüniD· 1 shared Christopher M. J. OsborneiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersPhysiology

Charlotte BuckleyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

VasoTracker 2: An Open-source Platform for Quantitative Analysis of Vascular Reactivity and Function

Matthew D. Lee, Christopher M. J. Osborne, Ross Stevenson, Amy MacDonald, Grace Ebner, Danielle A Jeffrey, Margaret MacDonald, Xun Zhang, Charlotte Buckley, Fabrice Dabertrand, Daniel R. Machin, Jason S. Au, Osama F. Harraz, Nathan Roger Tykocki, John G. McCarron, Calum Wilson

VasoTracker 2 provides open-source software and low-cost hardware for analyzing vascular reactivity and function across multiple imaging modalities.

bioRxiv · Apr 23, 2025 · PreprintPhysiology

Klebsiella pneumoniae disrupts vasodilation by targeting eNOS post translational modifications via the type VI secretion system and the capsule polysaccharide

Safi Rehman, Joana Sá‐Pessoa, Charlotte Buckley, Rebecca Lancaster, Ciara Ross, Xun Zhang, John G. McCarron, Tim M. Curtis, José Antonio Bengoechea

This study shows Klebsiella pneumoniae inhibits vasodilation by targeting eNOS post-translational modifications through its T6SS and capsule polysaccharide.

bioRxiv · Feb 5, 2025 · PreprintMicrobiology

Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension

Xun Zhang, Charlotte Buckley, Matthew D. Lee, Christine Salaün, Margaret MacDonald, Calum Wilson, John G. McCarron

This study shows that increased TRPV4 channel expression in endothelial cells both enhances and impairs vascular function in hypertension, leading to altered Ca2+ signaling and vascular reactivity.

Hypertension · Oct 23, 2024Peer-reviewedPhysiology