Author
Universitätsmedizin GöttingenORCID 0000-0001-8278-7668Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Hyun-Kyu Choi, Stefano Travaglino, Matthias Münchhalfen…·Cheng Zhu
This study shows that CD40-CD40L interactions form catch bonds that enhance B cell signaling and antibody class-switch, and mutations in CD40L disrupt this mechanism, causing X-linked Hyper IgM syndrome.
Joachim Maier, Daniel Sieme, Leo E Wong…·Christian Griesinger
The paper quantifies SH3-PRM interactions in SLP65/CIN85 complexes and models their phase separation behavior using LASSI, revealing an intramolecular interaction.
Daniel Sieme, Michael Engelke, Nasrollah Rezaei‐Ghaleh…·Christian Griesinger
This study identifies an intramolecular SH3:PRM interaction in CIN85 that modulates its valency and phase separation, affecting B cell activation.