Author

Cheng Zhu

Georgia Institute of TechnologyORCID 0000-0002-1718-565XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Amir Hossein Kazemipour AshkezariiD· 3 shared Menglan LiiD· 2 shared Peiwen CongiD· 2 shared Ameya Dravid· 1 shared Ankur K. SinghiD· 1 shared Deepali BalasubramaniiD· 1 shared Gabriel A. KwongiD· 1 shared Hyun-Kyu ChoiiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBioengineering

Amir Hossein Kazemipour AshkezariORCID

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Author profile →

3 papers

Recent·Most cited

SynNotch receptors for visualizing immunoreceptor force transmission and downstream signaling in vivo

Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir Hossein Kazemipour Ashkezari, Hyun-Kyu Choi, Gabriel A. Kwong, Ankur K. Singh, Cheng Zhu

This study develops SynNotch reporters to visualize force transmission and downstream signaling in immunoreceptors in vivo, showing force acts as a co-stimulus for CD40 and TCR signaling.

Advanced Science · Aug 25, 2026Peer-reviewedBioengineering

Evaluating the effects of CD8/CD4 on T cell function in terms of TCR-pMHC-coreceptor catch and slip bonds

Stefano Travaglino, Amir Hossein Kazemipour Ashkezari, Menglan Li, Valencia E. Watson, Peiwen Cong, Larissa Doudy, Hyun‐Kyu Choi, Cheng Zhu

This study evaluates how CD8/CD4 coreceptors affect T cell function by analyzing TCR-pMHC catch and slip bonds, finding that coreceptors enhance bond metrics and TCR sensitivity and specificity.

Frontiers in Immunology · Jun 5, 2026Peer-reviewedImmunology

DynMoCo: a Novel AI Framework to Reveal Modular Substructures of Protein From Molecular Dynamics

Lingchao Mao, Mingu Kwak, Amir Hossein Kazemipour Ashkezari, Zhenhai Li, Peiwen Cong, Yunfeng Chen, Jung Hun Phee, Sooyeon Kang, Jing Li, Cheng Zhu

DynMoCo identifies modular substructures in protein dynamics from molecular simulations by detecting time-evolving communities of residues.

Biophysical Journal · Mar 19, 2026Peer-reviewedBiophysics