Ludwig Knabl

The paper investigates the heritability and transcriptional impact of JAK3, STAT5A, and STAT6 variants in a Tyrolean family, finding that some carriers show activated basal transcriptomes without clinical symptoms.

This study develops a dual-chimeric virus to safely study antiviral resistance and cross-resistance using spike and protease inhibitors.

This study evaluates real-time metagenomic next-generation sequencing (rt-mNGS) for pathogen detection in respiratory samples, showing non-inferiority to culture methods with higher sensitivity and timely results.

The paper provides sequencing depth guidelines for comprehensive alternative splicing analysis across tissues, showing that current depths are insufficient and recommending deeper sequencing or long-read technologies.

The paper uses bulk RNA-seq to analyze immune responses to SARS-CoV-2 variants, showing that 10 million reads per sample can estimate immune cell composition and BCR/TCR sequences.