Author

Katherine A. Hamel

University of MinnesotaORCID 0000-0001-8294-2285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Carrie A. Sheeler· 2 shared Juao‐Guilherme S RosaiD· 2 shared Marija CvetanovićiD· 2 shared Stephen GilliatiD· 2 shared Alyssa SolesiD· 1 shared Ella Borgenheimer· 1 shared Ferris J. Ghannoum· 1 shared Francisco Emmanuel Labrada-MoncadaiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Carrie A. Sheeler

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2 papers

Recent·Most cited

NeuroscienceCellsPeer-reviewedOct 21, 2022

Spatial and temporal diversity of astrocyte phenotypes in Spinocerebellar ataxia type 1 mice

Juao‐Guilherme S Rosa, Katherine A. Hamel, Carrie A. Sheeler…·Marija Cvetanović

This study examines spatiotemporal changes in astrocyte phenotypes in SCA1 mice, finding region-specific alterations in astrocyte function and homeostasis that may contribute to disease progression.

19 citations

mousescRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 24, 2022

Increased vulnerability of Purkinje cells in the posterior cerebellum of SCA1 mice is associated with molecular and cellular alterations related to disease pathology

Katherine A. Hamel, Francisco Emmanuel Labrada-Moncada, Carrie A. Sheeler…·Marija Cvetanović

The paper identifies regional transcriptional and physiological differences in Purkinje cells of the cerebellum in SCA1 mice, showing reduced heterogeneity and increased vulnerability in the posterior cerebellum.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky