Author

Carrie A. Sheeler

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marija CvetanovićiD· 3 shared Alyssa SolesiD· 2 shared Hillary P. HandleriD· 2 shared Juao‐Guilherme S RosaiD· 2 shared Katherine A. HameliD· 2 shared Orion RainwateriD· 2 shared Stephen GilliatiD· 2 shared Adam Roszczyk· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Marija CvetanovićORCID

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4 papers

Recent·Most cited

A FMRF-amide peptide that regulates cell non-autonomous protein homeostasis in C. elegans.

Carrie A. Sheeler, Jacqueline Y. Lo, Daviana Menendez Escalera, Emmett Griffin‐Baldwin, Karmen Mah, Adam Roszczyk, Antoine E. Roux, Cynthia J. Kenyon, Jennifer L. Garrison, Ashley E. Frakes

This study identifies FLP-17, a neuropeptide that mediates cell non-autonomous UPRER activation in C. elegans, protecting against ER stress and protein aggregation.

bioRxiv · Mar 14, 2025 · PreprintNeuroscience

Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse

Lisa A. Duvick, William M. Southern, Kellie A. Benzow, Zoe N. Burch, Hillary P. Handler, Jason S. Mitchell, Hannah Kuivinen, Udaya Keerthy Gadiparthi, Praseuth Yang, Alyssa Soles, Carrie A. Sheeler, Orion Rainwater, Shannah Serres, Erin B. Lind, Tessa Nichols‐Meade, , Harry T. Orr

This study identifies brain regions and cell types contributing to SCA1 disease using conditional knockout mice, showing that targeting multiple areas and muscle is necessary for effective therapy.

bioRxiv · Feb 8, 2023 · PreprintNeuroscience

Spatial and temporal diversity of astrocyte phenotypes in Spinocerebellar ataxia type 1 mice

Juao‐Guilherme S Rosa, Katherine A. Hamel, Carrie A. Sheeler, Ella Borgenheimer, Stephen Gilliat, Alyssa Soles, Ferris J. Ghannoum, Kaelin Sbrocco, Hillary P. Handler, Orion Rainwater, Ryan Kang, Marija Cvetanović

This study examines spatiotemporal changes in astrocyte phenotypes in SCA1 mice, finding region-specific alterations in astrocyte function and homeostasis that may contribute to disease progression.

Cells · Oct 21, 2022Peer-reviewedNeuroscience

Increased vulnerability of Purkinje cells in the posterior cerebellum of SCA1 mice is associated with molecular and cellular alterations related to disease pathology

Katherine A. Hamel, Francisco Emmanuel Labrada-Moncada, Carrie A. Sheeler, Juao‐Guilherme S Rosa, Stephen Gilliat, Ying Zhang, Marija Cvetanović

The paper identifies regional transcriptional and physiological differences in Purkinje cells of the cerebellum in SCA1 mice, showing reduced heterogeneity and increased vulnerability in the posterior cerebellum.

bioRxiv · Feb 24, 2022 · PreprintNeuroscience