Cerebellar contribution to cognitive deficits and prefrontal cortex dysfunction in Spinocerebellar Ataxia Type 1 (SCA1)
Kaelin Sbrocco, Ella Borgenheimer, Ying Zhang, Mike Koob, Marija Cvetanović
This study investigates how cerebellar dysfunction in SCA1 affects prefrontal cortex function and cognition, finding that cerebellar degeneration can both impair and ameliorate PFC dysfunction depending on disease context.
bioRxiv · Jul 10, 2024 · PreprintNeuroscience