Viji M. Draviam

This study identifies PI(3)P binding to the 53BP1 tBRCT domain as essential for promoting 53BP1 condensate-like assembly at DNA double-strand breaks.

This study shows dynein and EB1 work together to regulate astral microtubule growth and spindle positioning, independent of dynein's classical cortical pulling role.

This study uses FRAP-SR to reveal subcompartments within 53BP1 foci, showing differential protein mobility and function in different foci types.

The paper introduces Multi-SpinX, an AI framework that extends SpinX to track mitotic spindles and kinetochores in multicellular environments across different mitotic stages.