James Dunham

The paper identifies WDR neuron inhibition as the mechanism by which tapentadol modulates spinal SEPs, supporting their use as a biomarker of spinal nociceptive processing.

This paper develops mechanically stable multi-electrode neural probes for high-resolution, multichannel recordings in peripheral nerves, improving signal yield and performance compared to single-electrode probes.

This study assesses the effects of lacosamide, pregabalin, and tapentadol on the rat spinal N1 somatosensory evoked potential to evaluate their analgesic mechanisms.

The paper evaluates supervised spike sorting for noisy single-electrode recordings from human C-nociceptors, finding raw signal features outperform complex methods and recommending tailored approaches.

The paper uses machine learning to analyze single-trial laser evoked potentials (LEPs) in rats, identifying distinct Aδ- and C-fibre mediated responses that predict pain behavior.