Polina Georgieva

The paper identifies host-targeting antivirals against SARS-CoV-2 using morphological profiling, finding compounds that reverse infected cell phenotypes and validate host processes hijacked by viruses.

This paper introduces a method to apply Cell Painting to 3D spheroids for morphological profiling, detecting phenotypic changes in colorectal cancer cells under compound treatments.

This study compares the predictive performance of models trained on fluorescence and brightfield images for drug mechanism of action prediction, finding comparable results.