Author

Shom Goel

The University of MelbourneORCID 0000-0001-8329-9084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:CUT&Tag· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alicia OshlackiD· 2 shared Antonio AhniD· 2 shared Catherine BlythiD· 2 shared April C. S. WattiD· 1 shared Aziz M. Al’KhafajiiD· 1 shared Belinda PhipsoniD· 1 shared Brendan RussiD· 1 shared Calandra V GrimaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioinformatics

Alicia OshlackORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Closing the fusion-detection gap in single-cell RNA-seq with a scalable, probe-based workflow

Jovana Maksimovic, Victoria Streeton-Cook, Calandra V Grima, Diane T. Hanna, Noura Tawfic, Louise E. A. Ludlow, Lauren M. Brown, Paul G. Ekert, Sara Alaei, David Yoannidis, Hansen J. Kosasih, Deborah L. White, Antonio Ahn, Shom Goel, Seong Lin Khaw, , Teresa Sadras

The paper introduces a probe-based workflow to detect oncogenic gene fusions in single-cell RNA-seq, validated in cancer cell lines and pediatric B-ALL cohorts.

bioRxiv · Aug 29, 2026 · PreprintBioinformatics

Benchmarking normalisation methods for differential binding analysis in CUT&RUN

Krutika Ambani, Antonio Ahn, April C. S. Watt, Catherine Blyth, Brendan Russ, Michael Taylor, Shom Goel, Alicia Oshlack

This study benchmarks normalization methods for differential binding analysis in CUT&RUN, finding data-driven normalization to be most robust and highlighting variable performance of spike-in normalization.

bioRxiv · May 25, 2026 · PreprintBioinformatics

Extraction and quantification of lineage-tracing barcodes with NextClone and CloneDetective

Givanna Putri, Nichelle Pires, N. Davidson, Catherine Blyth, Aziz M. Al’Khafaji, Shom Goel, Belinda Phipson

The paper introduces NextClone and CloneDetective for extracting and quantifying lineage-tracing barcodes from scRNA-seq and DNA sequencing data.

bioRxiv · Nov 19, 2023 · PreprintBioinformatics