jazzPanda: spatially aware marker gene detection for imaging-based spatial transcriptomics
Xinyi Jin, Givanna Putri, Jinming Cheng, Marie-Liesse Asselin-Labat, Gordon K. Smyth, Belinda Phipson
Binning transcript and cell coordinates into spatial vectors lets jazzPanda call smaller, spatially concordant marker sets than Wilcoxon or t-tests on Xenium/CosMx data, while modelling replicates and negative-control background.
bioRxiv · Aug 6, 2026 · PreprintBioinformatics✦ In-depth digest