Author

Ziyue Dong

University of Colorado BoulderORCID 0000-0001-8332-9212Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:simulation· 1

Frequent Co-Authors

Dean OldhamiD· 1 shared Emma E LietzkeiD· 1 shared Kayla G. SprengeriD· 1 shared Kimberley D. BruceiD· 1 shared Mary S. Rouse· 1 shared Robert H. EckeliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Dean OldhamORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintNov 20, 2025

Lipoprotein lipase requires a flexible lid and stable C-terminal, both maintained by ApoC-II peptide binding

Emma E Lietzke, Mary S. Rouse, Dean Oldham…·Kimberley D. Bruce

This study uses molecular dynamics simulations and biochemical assays to show that ApoC-II peptide binding stabilizes LPL's structure and regulates its activity through lid flexibility and CTD flipping.

DOI 10.1101/2025.11.20.689556

simulation

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