Tomoya Mizukoshi

This study shows that Nwd1 knockout mice develop NASH-like liver pathology due to SERCA2 dysfunction and ER stress.

This study investigates the spatiotemporal regulation of de novo and salvage purine synthesis during brain development and finds that their utilization shifts from de novo in embryonic stages to salvage in postnatal-adult stages, with implications for mTOR signaling and brain morphology.

This study identifies Inka2 as a Pak4 inhibitor that regulates actin dynamics in neuronal development by promoting depolymerization and inhibiting protrusion formation.