Author

Jason M. Brenchley

National Institutes of HealthORCID 0000-0001-8357-2984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Honghui WangiD· 2 shared Joseph A. KovacsiD· 2 shared Liang MaiD· 2 shared Lisa R. Bishop· 2 shared Melanie T. CushioniD· 2 shared Ousmane H. CisséiD· 2 shared Yueqin LiuiD· 2 shared Alice LatinneiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Honghui WangORCID

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3 papers

Recent·Most cited

Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance

Megan M. Dunagan, Nathânia Dábilla, Colton M McNinch, Jason M. Brenchley, Patrick Dolan, Julie M. Fox

This study shows that activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance and prevent monocytes from being infected.

PLoS Pathogens · Feb 24, 2025Peer-reviewedImmunology

Regional Centromere Configuration in the Fungal Pathogens of Pneumocystis Genus

Ousmane H. Cissé, Shelly J. Curran, Hernan Diego Folco, Yueqin Liu, Lisa R. Bishop, Honghui Wang, Elizabeth R. Fischer, Anne Sally Davis, Spenser J. Babb-Biernacki, Vinson Patrick Doyle, Jonathan K. Richards, Sergio A. Hassan, John P. Dekker, Pavel P. Khil, Jason M. Brenchley, , Joseph A. Kovacs

The paper identifies short, epigenetic centromeres in Pneumocystis species using ChIP-Seq and shows they differ from S. pombe centromeres despite evolutionary proximity.

mBio · Feb 21, 2024Peer-reviewedGenomics

Diversity and complexity of the large surface protein family in the compacted genomes of various Pneumocystis species

Liang Ma, Zehua Chen, Da Wei Huang, Ousmane H. Cissé, Jamie L. Rothenburger, Alice Latinne, Lisa R. Bishop, Robert V. Blair, Jason M. Brenchley, Magali Chabé, Xilong Deng, Vanessa M. Hirsch, Rebekah I. Keesler, Geetha Kutty, Yueqin Liu, , Joseph A. Kovacs

The paper characterizes the diversity and evolution of the Msg gene superfamily across Pneumocystis species, revealing its functional roles in immune evasion and host adaptation.

bioRxiv · Oct 25, 2019 · PreprintMolecular Biology